TISSUE IN A PLANT STEM CROSSWORD SKIN
TISSUE IN A PLANT STEM CROSSWORD PATCH

Similarly, a developing tree’s embryonic root bores its way into the soil during seed germination.

TISSUE IN A PLANT STEM CROSSWORD SKIN

In this way, they act as an anchor and reservoir to support skin development and repair. It’s the phase of the hair cycle that is most conducive to promoting healing.” Skin injury causes cells to stream out from hair follicles to repair the wound, recapitulating the role of hair follicles during skin embryogenesis. “Stem cells are activated, and growth factors are being produced. He explained that skin injuries that occur during the anagen phase of hair growth heal twice as quickly as when follicles are in their resting stage. “This is the first clear demonstration that you can transplant hair follicles into a mature scar and get some kind of outcome,” said Matthew Hardman, a professor and chair of wound healing at the University of Hull, who was not involved in this study.

Higgins’ team obtained skin biopsies from these scars and compared the tissue before and up to six months after anagen hair follicle transplantation. The hair follicles were taken from the patients’ own scalps and transplanted during anagen-the active phase of hair growth characterized by stem cell proliferation and migration, and the release of signaling molecules. Higgins and her team recruited three patients from a hair transplantation clinic who underwent routine hair follicle transplantation to conceal surgical scalp scars from previous transplant procedures. To learn more, listen to this Science Philosophy in a Flash mini podcast, 'A Surprising Way to Repair Scar Tissue' Although scar tissue is a byproduct of repair, it can severely limit skin function, causing contraction, pain, reduced sensation, and restricted mobility. “There are huge functional consequences to some types of scarring,” Cotsarelis said. Fibrotic scars have pathological features, including a thin epidermis, thick connective tissue, and a low density of blood vessels and nerves, which extend far below the surface of the skin. George Cotsarelis, a physician, professor, and chair of dermatology at the University of Pennsylvania, who was not involved in this study, explained that skin injury-due to burns, surgical incisions, or traumatic injuries-induces fibrotic scarring, despite the well-orchestrated cascade of biochemical and cellular mechanisms that drive wound repair.

“They told us that when they do eyebrow transplants, the scar tissue around it will also look better.” Higgins and her team decided to take a deeper look below the skin’s surface to understand how follicle transplants change the architecture of scarred skin tissue. 4 “Hair transplant surgeons already use this for scarring on the head or face,” Higgins said. In a recent study published in npj Regenerative Medicine, Claire Higgins, a professor of bioengineering at Imperial College London, and her team performed a pilot clinical study in which they transplanted hair follicles into human skin scars. Besides the cosmetic advantages, researchers are discovering that transplanted hair follicles also remodel scarred skin to create functional tissue, much like transplanted trees transform previously barren soil. Hair transplantation augments hair loss caused by baldness or skin injury. Similarly, hair transplant surgeons remodel the terrain of the human scalp, planting hair follicles like trees in a forest. 1-3 In this way, arborists and foresters reestablish the ecological function of degraded landscapes.

A tree’s roots exude chemicals and signaling molecules that remodel the soil to stimulate further growth.

TISSUE IN A PLANT STEM CROSSWORD PATCH

The roots of a single tree can transform a barren patch of forest floor into a thriving subterranean ecosystem.

Tissue in a plant stem crossword